Benefits and Meaning of Lipids Profile in Relation to Oxidative Balance and Brain Morphology in Schizophrenia

Schizophrenia is characterized by complex metabolic dysregulations and their consequences. Until now, numerous theories have explained its pathogenesis, using a spectrum of available technologies. We focused our interest on lipid profile—periphery high-density cholesterol level lipoproteins in the human brain compared magnetic resonance imaging (MRI) scans patients with schizophrenia healthy group. Detailed analysis biochemical parameters was performed spectroscopy. Our study aimed to reveal correlations between periphery levels brain, depicted MRI scans, peripheral oxidative stress expressed as paraoxonase. Patients decreased lipoproteins, low paraoxonase activity, slightly raised sodium blood. Positive significant serum anterior cingulate cortex, unique area for pathophysiology, MR spectroscopy signals, diffusion been revealed. To knowledge, this first describe effect an disorder development schizophrenia.